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BMJ:刷牙不当患癌风险提高80%

Tags: 刷牙   患癌   BMJ      作者:佚名 更新:2013-03-27

  《英国医学杂志》研究发现:口腔不干净可能导致短命,刷牙不当易导致牙菌斑或口腔病菌过多,进而使患癌早亡危险增加80%,寿命减少13年。

  口腔不干净不仅会影响形象,还可能导致短命。口腔感染还会引发炎症,通过损伤的牙龈进进入血液,让心脏受损引发多种疾病。可按日本牙齿健康自测表检查自己的牙齿。

  瑞典科学家自1985年开始对随机抽取的1390名斯德哥尔摩参试者进行了为期24年的跟踪研究。研究开始时,参试者年龄在30—40岁之间。研究人员对参试者进行了问卷调查,调查内容涉及吸烟等癌症风险因素。研究人员还测试了参试者口腔健康状况,以确定是否存在牙菌斑、牙周病及牙齿脱落等问题。一些参试者没有严重牙周病,但是存在不同程度的牙菌斑问题。到2009年,58名参试者死亡,死亡者中,因癌症死亡的占35%。而这些人中,大多患有牙菌斑牙周病。在将年龄、吸烟等因素排除后,口腔健康与早亡间的关系仍然存在。

  研究者指出,口腔感染可能会引发炎症,炎症通过损伤的牙龈进进入血液,进而让心脏受损,引发多种疾病。


The association of dental plaque with cancer mortality in Sweden. A longitudinal study
Objectives 
To study whether the amount of dental plaque, which indicates poor oral hygiene and is potential source of oral infections, associates with premature death from cancer.
Design 
Prospective cohort study.
Participants 
1390 randomly selected healthy young Swedes followed up from 1985 to 2009. All subjects underwent oral clinical examination and answered a questionnaire assessing background variables such as socioeconomic status and smoking.
Outcome measures 
Causes of death were recorded from national statistics and classified according to the WHO International Classification of Diseases. Unpaired t test, χ2 tests and multiple logistic regressions were used.
Results 
Of the 1390 participants, 4.2% had died during the follow-up. Women had died at a mean age of 61.0 (±2.6 SD) years and men at the age of 60.2 (±2.9 SD) years. The amount of dental plaque between those who had died versus survived was statistically significant (p<0.001). In multiple logistic regression analysis, dental plaque appeared to be a significant independent predictor associated with 1.79 times the OR of death (p<0.05). Age increased the risk with an OR of 1.98 (p<0.05) and gender (men) with an OR of 1.91 (p<0.05). The malignancies were more widely scattered in men, while breast cancer was the most frequent cause of death in women.
Conclusions 
This study hypothesis was confirmed by showing that poor oral hygiene, as reflected in the amount of dental plaque, was associated with increased cancer mortality.

    

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