罗氏收购忙，4.7亿欧元收购法国Trophos

罗氏近日以4.7亿欧元收购法国Trophos。

Trophos是一家私人持股的生物技术公司，位于法国的马赛市。Trophos曾研发过olesoxime，目前正在研究该药对治疗脊髓性肌萎缩症的作用。脊髓性肌萎缩症是一种罕见的遗传性神经肌肉疾病，最常见于儿童。2期临床试验结果表明，olesoxime能够有效地维持神经肌肉功能，并且能够减少并发症。

根据合同条约，Trophos的股东将会获得1.2亿欧元的预付款和高达3.5亿美元的olesoxime里程金。

罗氏的首席医疗官Sandra Horning表示，罗氏将会在Trophos和法国肌肉萎缩症协会的工作基础上进一步展开olesoxime的研发工作。该药物在欧洲和美国都享有孤儿药的地位。

近来罗氏收购不断，这是继花费10亿美元收购Foundation Medicine后的新动作。此外，罗氏还在一桩交易中与日本明治制药和加拿大Fedora合作，针对抗生素耐药性的早期治疗，该合同价值7.5亿美元。

原文

Roche buys France's Trophos in 470 million euro deal

Roche has hit the acquisition trail to buy France’s Trophos in a deal that could be worth 470 million euros.

Trophos， a privately-held biotech based in Marseille， France， has developed olesoxime， which is being developed for spinal muscular atrophy – a rare and debilitating genetic neuromuscular disease that is most commonly diagnosed in children. Results from a Phase II trial have shown a beneficial effect on the maintenance of neuromuscular function and a reduction in medical complications associated with the disease.

Under the terms of the agreement， Trophos’ shareholders will receive 120 million euros upfront and up to 350 million euros based on achievement of predetermined milestones.

Roche’s chief medical officer Sandra Horning said “we will build on the work done by Trophos and the French Muscular Dystrophy Association to advance the development of olesoxime and to bring it to people who live with this devastating condition as quickly as possible”. The compound has orphan drug status on both sides of the Atlantic.

The deal rounds off a busy week for Roche， which has paid over $1 billion to acquire a majority stake in molecular information company Foundation Medicine. The Swiss giant licensed an early-stage treatment for antibiotic resistance from Japan’s Meiji Seika Pharma and Fedora of Canada in a deal that could be worth $750 million.