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医学量表、计算器 / 肝病 / 性别公平肝分配模型(GEMA-Na)

性别公平肝分配模型(GEMA-Na)

1.性别
2.年龄
3.肌酐(μmol/L)
4.尿素水平(mmol/L)
5.INR
6.胆红素水平(μmol/L)
7.Na离子水平(mmol/L)
8.中重度腹水
皇家自由医院肾小球滤过率(RFH-GFR): ml/min
肝脏分配的性别平等模型(GEMA):
肝脏分配的性别平等模型-Na(GEMA-Na):
MELD 3.0无白蛋白得分:
MELD得分:
MELD-Na得分:
注:
1.GEMA 模型和 GEMA-Na 模型比 MELD 和 MELD-Na 评分更能预测 90 天内的死亡或因临床恶化.
2.RFH-GFR was calculated at inclusion in the waiting list according to the original formula: 45·9 × (creatinine^–0·836) × (urea^–0·229) × (INR^–0·113) × (age^–0·129) × (sodium0·972) × 0·809 (if female) × 0·92 (if moderate or severe ascites).
GEMA model according to generalised additive multivariable Cox regression was expressed as: GEMA=3·777 × ln(Bilirubin) + 7·883 × ln(INR) – 8·306 × ln(RFH-GFR) + 31·932
The equation of GEMA-Na after including the correction by serum sodium was expressed as: GEMA-Na=GEMA − Na − [0·025 × GEMA × (140 − Na)] + 140
相关评分:
终末肝脏病评分3.0 (MELD 3.0美版)
终末期肝病预后模型(MELD评分)
酒精性肝炎重症和预后评分(ABIC评分,MELD评分)
终末期肝病MELD评分(透析人群)
儿童终末期肝病PELD评分
参考文献:
Rodríguez-Perálvarez ML, de la Rosa G, Gómez-Orellana AM, Aguilera MV, Pascual Vicente T, Pereira S, Ortiz ML, Pagano G, Suarez F, González Grande R, Cachero A, Tomé S, Barreales M, Martín Mateos R, Pascual S, Romero M, Bilbao I, Alonso Martín C, Otón E, González Diéguez L, Espinosa MD, Arias Milla A, Blanco Fernández G, Lorente S, Cuadrado Lavín A, Redín García A, Sánchez Cano C, Cepeda-Franco C, Pons JA, Colmenero J, Guijo-Rubio D, Otero A, Amador Navarrete A, Romero Moreno S, Rodríguez Soler M, Hervás Martínez C, Gastaca M. GEMA-Na and MELD 3.0 severity scores to address sex disparities for accessing liver transplantation: a nationwide retrospective cohort study. EClinicalMedicine. 2024 Jul 18;74:102737. doi: 10.1016/j.eclinm.2024.102737
Rodríguez-Perálvarez ML, Gómez-Orellana AM, Majumdar A, Bailey M, McCaughan GW, Gow P, Guerrero M, Taylor R, Guijo-Rubio D, Hervás-Martínez C, Tsochatzis EA.Development and validation of the Gender-Equity Model for Liver Allocation (GEMA) to prioritise candidates for liver transplantation: a cohort study. Lancet Gastroenterol Hepatol. 2023 Mar;8(3):242-252. doi: 10.1016/S2468-1253(22)00354-5
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