Notch1-话题@MedSci

#Notch1#

10篇内容 | 1476人围观

关注话题

话题活跃用户

#插入话题

插入图片

最新最热

[GetTopicListResponse(id=2261773, encodeId=25dd2261e73ae, content=<a href='/topic/show?id=5df56936690' target=_blank style='color:#2F92EE;'>#生物标志物#</a> <a href='/topic/show?id=b860101129ac' target=_blank style='color:#2F92EE;'>#食管鳞状细胞癌#</a> <a href='/topic/show?id=29a6129e299' target=_blank style='color:#2F92EE;'>#Notch1#</a> <a href='/topic/show?id=e555603625e' target=_blank style='color:#2F92EE;'>#替雷利珠单抗#</a>, objectTitle=JCO：沈琳教授团队发现NOTCH1突变显著预测替雷利珠单抗在晚期食管鳞癌中的生存获益, objectType=article, longId=873195, objectId=e80b8e319548, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20250423/1745437649583_4754896.jpg, objectUrl=/article/show_article.do?id=e80b8e319548, replyNumber=0, likeNumber=19, createdTime=2025-04-24, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=威斯康星, moduleDTOList=[ModuleDTO(moduleId=e80b8e319548, moduleTitle=JCO：沈琳教授团队发现NOTCH1突变显著预测替雷利珠单抗在晚期食管鳞癌中的生存获益, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=e80b8e319548)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2248843, encodeId=92ac22488435b, content=<a href='/topic/show?id=493ae869206' target=_blank style='color:#2F92EE;'>#结直肠癌#</a> <a href='/topic/show?id=29a6129e299' target=_blank style='color:#2F92EE;'>#Notch1#</a> <a href='/topic/show?id=5f9512349931' target=_blank style='color:#2F92EE;'>#DUSP6#</a>, objectTitle=Nat Commun：揭示蛋白DUSP6促进结直肠癌生长机制, objectType=article, longId=860185, objectId=c81a86018521, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/bioon-com/20250118/1737175086990_2185383.png, objectUrl=/article/show_article.do?id=c81a86018521, replyNumber=0, likeNumber=15, createdTime=2025-01-20, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=0, avatar=, status=0, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=null, followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2248276, encodeId=6d0422482e6cf, content=<a href='/topic/show?id=29a6129e299' target=_blank style='color:#2F92EE;'>#Notch1#</a> <a href='/topic/show?id=9ba323214c9' target=_blank style='color:#2F92EE;'>#主动脉病变#</a>, objectTitle=Nature子刊：复旦大学张炜佳团队纠正线粒体丢失的干预策略，显著减轻小鼠NOTCH1相关的主动脉病变！, objectType=article, longId=859378, objectId=31128593e838, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20250115/1736939919529_8538692.png, objectUrl=/article/show_article.do?id=31128593e838, replyNumber=0, likeNumber=34, createdTime=2025-01-16, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=陕西省, moduleDTOList=[ModuleDTO(moduleId=31128593e838, moduleTitle=Nature子刊：复旦大学张炜佳团队纠正线粒体丢失的干预策略，显著减轻小鼠NOTCH1相关的主动脉病变！, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=31128593e838)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2238065, encodeId=e5b922380651b, content=<a href='/topic/show?id=12192862494' target=_blank style='color:#2F92EE;'>#先天性心脏病#</a> <a href='/topic/show?id=29a6129e299' target=_blank style='color:#2F92EE;'>#Notch1#</a>, objectTitle=Nat Commun 赵健元/陶辉/桂永浩/王凤合作团队揭示NOTCH1线粒体定位在心脏发育中的关键作用, objectType=article, longId=851739, objectId=d86a851e39cd, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20241119/1732004856332_8538692.png, objectUrl=/article/show_article.do?id=d86a851e39cd, replyNumber=0, likeNumber=53, createdTime=2024-11-20, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=陕西省, moduleDTOList=[ModuleDTO(moduleId=d86a851e39cd, moduleTitle=Nat Commun 赵健元/陶辉/桂永浩/王凤合作团队揭示NOTCH1线粒体定位在心脏发育中的关键作用, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=d86a851e39cd)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2237581, encodeId=b072223e58168, content=<a href='/topic/show?id=12192862494' target=_blank style='color:#2F92EE;'>#先天性心脏病#</a> <a href='/topic/show?id=29a6129e299' target=_blank style='color:#2F92EE;'>#Notch1#</a>, objectTitle=赵健元/陶辉/桂永浩/王凤合作《自然·通讯》：揭示NOTCH1线粒体定位在心脏发育中的关键作用, objectType=article, longId=851613, objectId=8b7c85161390, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20240509/1715220943225_5579292.png, objectUrl=/article/show_article.do?id=8b7c85161390, replyNumber=0, likeNumber=57, createdTime=2024-11-18, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=8b7c85161390, moduleTitle=赵健元/陶辉/桂永浩/王凤合作《自然·通讯》：揭示NOTCH1线粒体定位在心脏发育中的关键作用, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=8b7c85161390)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=1958621, encodeId=75ab1958621b0, content=<a href='/topic/show?id=29a6129e299' target=_blank style='color:#2F92EE;'>#Notch1#</a>, objectTitle=Nat Commun：RFC4/Notch1正反馈回路可促进非小细胞肺癌的转移和干细胞特性, objectType=article, longId=212434, objectId=a541212434d9, topicUrl=null, isHasObj=0, objectCover=null, objectUrl=/article/show_article.do?id=a541212434d9, replyNumber=0, likeNumber=106, createdTime=2022-01-10, rootId=0, userName=drwjr, userId=08e964, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=a541212434d9, moduleTitle=Nat Commun：RFC4/Notch1正反馈回路可促进非小细胞肺癌的转移和干细胞特性, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=a541212434d9)], followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=1958620, encodeId=7605195862006, content=<a href='/topic/show?id=29a6129e299' target=_blank style='color:#2F92EE;'>#Notch1#</a>, objectTitle=Blood：活化的AKT通过过度激活Notch1触发CLL→Richter转化, objectType=article, longId=203476, objectId=91592034e6b8, topicUrl=null, isHasObj=0, objectCover=null, objectUrl=/article/show_article.do?id=91592034e6b8, replyNumber=0, likeNumber=0, createdTime=2021-04-25, rootId=0, userName=drwjr, userId=08e964, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=91592034e6b8, moduleTitle=Blood：活化的AKT通过过度激活Notch1触发CLL→Richter转化, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=91592034e6b8)], followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=1958619, encodeId=5a4d1958619fe, content=<a href='/topic/show?id=29a6129e299' target=_blank style='color:#2F92EE;'>#Notch1#</a>, objectTitle=Nat Commun：厦门大学邓初夏团队：NOTCH1激活促进三阴性乳腺癌形成, objectType=article, longId=196680, objectId=48c7196680b0, topicUrl=null, isHasObj=0, objectCover=null, objectUrl=/article/show_article.do?id=48c7196680b0, replyNumber=0, likeNumber=114, createdTime=2021-01-10, rootId=0, userName=docwu2019, userId=a12645, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=48c7196680b0, moduleTitle=Nat Commun：厦门大学邓初夏团队：NOTCH1激活促进三阴性乳腺癌形成, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=48c7196680b0)], followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=1958617, encodeId=8aa9195861eae, content=<a href='/topic/show?id=29a6129e299' target=_blank style='color:#2F92EE;'>#Notch1#</a>, objectTitle=Aging：miR-34b的异常甲基化通过靶向Notch1参与调节血管钙化, objectType=article, longId=188922, objectId=512c188922bb, topicUrl=null, isHasObj=0, objectCover=null, objectUrl=/article/show_article.do?id=512c188922bb, replyNumber=0, likeNumber=105, createdTime=2020-12-04, rootId=0, userName=drwjr, userId=08e964, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=512c188922bb, moduleTitle=Aging：miR-34b的异常甲基化通过靶向Notch1参与调节血管钙化, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=512c188922bb)], followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=1958618, encodeId=eeb619586186c, content=<a href='/topic/show?id=29a6129e299' target=_blank style='color:#2F92EE;'>#Notch1#</a>, objectTitle=Cell Death Dis：肿瘤微环境浸润B细胞通过IL-1β/HIF-2α/ Notch1信号促进肾癌转移, objectType=article, longId=190441, objectId=8ef8190441e0, topicUrl=null, isHasObj=0, objectCover=null, objectUrl=/article/show_article.do?id=8ef8190441e0, replyNumber=0, likeNumber=89, createdTime=2020-08-28, rootId=0, userName=drwjr, userId=08e964, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=8ef8190441e0, moduleTitle=Cell Death Dis：肿瘤微环境浸润B细胞通过IL-1β/HIF-2α/ Notch1信号促进肾癌转移, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=8ef8190441e0)], followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=1958614, encodeId=344219586141f, content=<a href='/topic/show?id=29a6129e299' target=_blank style='color:#2F92EE;'>#Notch1#</a>, objectTitle=J Cell Physiol：Notch1启动子甲基化通过Wnt /β-catenin信号通路介导人主动脉瓣间质细胞的成骨分化, objectType=article, longId=165163, objectId=a1ef165163d6, topicUrl=null, isHasObj=0, objectCover=null, objectUrl=/article/show_article.do?id=a1ef165163d6, replyNumber=0, likeNumber=101, createdTime=2020-03-03, rootId=0, userName=drwjr, userId=08e964, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=a1ef165163d6, moduleTitle=J Cell Physiol：Notch1启动子甲基化通过Wnt /β-catenin信号通路介导人主动脉瓣间质细胞的成骨分化, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=a1ef165163d6)], followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=1958615, encodeId=59221958615ee, content=<a href='/topic/show?id=29a6129e299' target=_blank style='color:#2F92EE;'>#Notch1#</a>, objectTitle=Mol Cancer Ther：Notch1活性缺失能够抑制前列腺癌的生长和转移, objectType=article, longId=166004, objectId=bb1e1660040e, topicUrl=null, isHasObj=0, objectCover=null, objectUrl=/article/show_article.do?id=bb1e1660040e, replyNumber=0, likeNumber=107, createdTime=2019-07-31, rootId=0, userName=drwjr, userId=08e964, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=bb1e1660040e, moduleTitle=Mol Cancer Ther：Notch1活性缺失能够抑制前列腺癌的生长和转移, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=bb1e1660040e)], followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=1958616, encodeId=729b19586166e, content=<a href='/topic/show?id=29a6129e299' target=_blank style='color:#2F92EE;'>#Notch1#</a>, objectTitle=J Cell Biochem：Notch1蛋白的抑制能够减少肿瘤生长, objectType=article, longId=167324, objectId=3f9816e324a3, topicUrl=null, isHasObj=0, objectCover=null, objectUrl=/article/show_article.do?id=3f9816e324a3, replyNumber=0, likeNumber=109, createdTime=2019-09-15, rootId=0, userName=drwjr, userId=08e964, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=3f9816e324a3, moduleTitle=J Cell Biochem：Notch1蛋白的抑制能够减少肿瘤生长, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=3f9816e324a3)], followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=1958613, encodeId=fad119586135c, content=<a href='/topic/show?id=29a6129e299' target=_blank style='color:#2F92EE;'>#Notch1#</a>, objectTitle=Blood：在CLL细胞中，FBXW7突变导致NOTCH1降解障碍而异常积累, objectType=article, longId=155326, objectId=e0d0155326ec, topicUrl=null, isHasObj=0, objectCover=null, objectUrl=/article/show_article.do?id=e0d0155326ec, replyNumber=0, likeNumber=91, createdTime=2019-02-06, rootId=0, userName=drwjr, userId=08e964, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=e0d0155326ec, moduleTitle=Blood：在CLL细胞中，FBXW7突变导致NOTCH1降解障碍而异常积累, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=e0d0155326ec)], followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=1958612, encodeId=67fd195861238, content=<a href='/topic/show?id=29a6129e299' target=_blank style='color:#2F92EE;'>#Notch1#</a>, objectTitle=【2017 ASH】凋亡抵抗以及NOTCH1基因状态对伊布替尼治疗预后的影响, objectType=article, longId=122935, objectId=add9122935f5, topicUrl=null, isHasObj=0, objectCover=null, objectUrl=/article/show_article.do?id=add9122935f5, replyNumber=0, likeNumber=79, createdTime=2017-12-26, rootId=0, userName=drwjr, userId=08e964, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=, moduleDTOList=[ModuleDTO(moduleId=add9122935f5, moduleTitle=【2017 ASH】凋亡抵抗以及NOTCH1基因状态对伊布替尼治疗预后的影响, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=add9122935f5)], followStatus=false, userIsMember=false, type=1, lengthMark=0)] 梅斯话题小助手

Notch1

2020-05-29

梅斯管理员 (审核中...)

前往app查看评论内容

#生物标志物# #食管鳞状细胞癌# #Notch1# #替雷利珠单抗#

JCO：沈琳教授团队发现NOTCH1突变显著预测替雷利珠单抗在晚期食管鳞癌中的生存获益

2025-04-24发表于威斯康星

梅斯管理员 (审核中...)

前往app查看评论内容

#结直肠癌# #Notch1# #DUSP6#

2025-01-20发表于上海

梅斯管理员 (审核中...)

前往app查看评论内容

#Notch1# #主动脉病变#

Nature子刊：复旦大学张炜佳团队纠正线粒体丢失的干预策略，显著减轻小鼠NOTCH1相关的主动脉病变！

2025-01-16发表于陕西省

梅斯管理员 (审核中...)

前往app查看评论内容

#先天性心脏病# #Notch1#

Nat Commun 赵健元/陶辉/桂永浩/王凤合作团队揭示NOTCH1线粒体定位在心脏发育中的关键作用

2024-11-20发表于陕西省

梅斯管理员 (审核中...)

前往app查看评论内容

#先天性心脏病# #Notch1#

赵健元/陶辉/桂永浩/王凤合作《自然·通讯》：揭示NOTCH1线粒体定位在心脏发育中的关键作用

2024-11-18发表于上海

drwjr (审核中...)

前往app查看评论内容

#Notch1#

Nat Commun：RFC4/Notch1正反馈回路可促进非小细胞肺癌的转移和干细胞特性

2022-01-10

drwjr (审核中...)

前往app查看评论内容

#Notch1#

Blood：活化的AKT通过过度激活Notch1触发CLL→Richter转化

2021-04-25

docwu2019 (审核中...)

前往app查看评论内容

#Notch1#

Nat Commun：厦门大学邓初夏团队：NOTCH1激活促进三阴性乳腺癌形成

2021-01-10

drwjr (审核中...)

前往app查看评论内容

#Notch1#

Aging：miR-34b的异常甲基化通过靶向Notch1参与调节血管钙化

2020-12-04

drwjr (审核中...)

前往app查看评论内容

#Notch1#

Cell Death Dis：肿瘤微环境浸润B细胞通过IL-1β/HIF-2α/ Notch1信号促进肾癌转移

2020-08-28

drwjr (审核中...)

前往app查看评论内容

#Notch1#

J Cell Physiol：Notch1启动子甲基化通过Wnt /β-catenin信号通路介导人主动脉瓣间质细胞的成骨分化

2020-03-03

drwjr (审核中...)

前往app查看评论内容

#Notch1#

Mol Cancer Ther：Notch1活性缺失能够抑制前列腺癌的生长和转移

2019-07-31

drwjr (审核中...)

前往app查看评论内容

#Notch1#

J Cell Biochem：Notch1蛋白的抑制能够减少肿瘤生长

2019-09-15

drwjr (审核中...)

前往app查看评论内容

#Notch1#

Blood：在CLL细胞中，FBXW7突变导致NOTCH1降解障碍而异常积累

2019-02-06

drwjr (审核中...)

前往app查看评论内容

#Notch1#

【2017 ASH】凋亡抵抗以及NOTCH1基因状态对伊布替尼治疗预后的影响

2017-12-26

科室
- - 订阅+
  - 更多科室
工具
服务