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#CRISPR#

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CRISPR

2020-05-29

lifestar (审核中...)

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全文收起这6名患儿在接受基于 #CRISPR##基因编辑#的 #CAR-T 细胞治疗#后，有4人在28天内病情缓解，这使他们能够接受#骨髓干细胞移植#，已重建健康的免疫系统。在这4人中，2人分别在治疗后9个月和18个月后处于持续缓解期，但遗憾的是，另外2人在干细胞移植后复发。仅仅编辑#CD19#，治标不治本，这种效果应该能想得到的，主要治疗仍然是靠骨髓干细胞移植起作用吧。

STM：CRISPR基因编辑的通用型CAR-T，治疗儿童白血病临床试验结果发布

2022-10-30

yuandd (审核中...)

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#CRISPR#

Nat Biotech：一次生产10亿CAR-T细胞，新型CRISPR技术，无需病毒载体高效插入超长DNA序列

2022-09-13

yuandd (审核中...)

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#CRISPR#

当心！Nat Commun发文：CRISPR/Cas9基因编辑可能导致细胞毒性和基因组不稳定性

2022-08-28

yuandd (审核中...)

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#CRISPR#

Science：可爱龙团队揭示能够切割蛋白的新型CRISPR工具的作用机制

2022-08-28

yuandd (审核中...)

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#CRISPR#

CRISPR Journal：领先David Liu一个月，吉林大学李占军/赖良学率先开发出单个AAV递送的碱基编辑器

2022-08-10

yuandd (审核中...)

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#CRISPR#

JACS：中科大梁好均团队开发基于CRISPR-dCas9的可编程转录调节器

2022-07-09

yuandd (审核中...)

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#CRISPR#

重磅发布！NEJM志公布首个体内 CRISPR 基因编辑治疗人类遗传疾病试验结果

2022-07-05

yuandd (审核中...)

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#CRISPR#

一次注射，长期有效，诺奖团队开发的LNP递送的体内CRISPR疗法最新临床数据给力

2022-06-28

yuandd (审核中...)

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#CRISPR#

Nature重磅：AAV递送CRISPR，体内改造B细胞，产生广泛中和抗体治疗艾滋病

2022-06-23

yuandd (审核中...)

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#CRISPR#

Editas基于CRISPR-Cas12a的β-地贫疗法获FDA孤儿药认证

2022-05-18

docwu2019 (审核中...)

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#CRISPR#

Nature Biomedical Engineering: 用魔法打败魔法？利用RNA干扰降低CRISPR在肝脏中的脱靶性

2022-04-17

docwu2019 (审核中...)

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#CRISPR#

张锋新论文：通过CRISPR激活筛选，发现癌症免疫治疗耐药性关键蛋白

2022-04-01

docwu2019 (审核中...)

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#CRISPR#

Nature Biomedical Engineering：武汉大学殷昊团队开发基于CRISPR的新冠快检技术，20分钟内精准检测新冠病毒

2022-03-25

docwu2019 (审核中...)

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#CRISPR#

Cell子刊：陈斯迪团队利用CRISPR筛选，发现增强CAR-T效果新手段

2022-03-14

docwu2019 (审核中...)

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#CRISPR#

Cell Metabolism：陈斯迪团队利用CRISPR筛选，发现增强CAR-T效果新手段

2022-03-13

docwu2019 (审核中...)

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#CRISPR#

Cell Research：舒易来等开发CRISPR/Cas9-HMEJ基因修复体系治疗隐性遗传性聋

2022-03-02

docwu2019 (审核中...)

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#CRISPR#

Nature Communications：意想不到：CRISPR基因编辑会导致可遗传的基因组结构突变

2022-02-10

docwu2019 (审核中...)

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#CRISPR#

Cell Reports：纳米颗粒助力，首次实现对血管内皮的CRISPR基因编辑

2022-01-07

docwu2019 (审核中...)

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#CRISPR#

STTT：高飞/李铮等揭示男性无精症致病基因，并通过CRISPR基因编辑进行修复

2022-01-07

docwu2019 (审核中...)

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#CRISPR#

展望2022：受期待的11项临床试验，从CRISPR、裸盖菇素，到溶瘤病毒

2021-12-24

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