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style='color:#2F92EE;'>#自噬#</a> <a href='/topic/show?id=cd96535608c' target=_blank style='color:#2F92EE;'>#慢性炎症#</a> <a href='/topic/show?id=ad3e128318cd' target=_blank style='color:#2F92EE;'>#WSTF蛋白#</a>, objectTitle=Nature：慢性炎症“元凶”现形！WSTF蛋白核自噬的双面人生, objectType=article, longId=885238, objectId=71868852388f, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/bioon-com/20250703/1751518097076_1938376.png, objectUrl=/article/show_article.do?id=71868852388f, replyNumber=0, likeNumber=6, createdTime=2025-07-03, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=0, avatar=, status=0, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=null, followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2263659, encodeId=6dd022636596c, content=<a href='/topic/show?id=21d33e36181' target=_blank style='color:#2F92EE;'>#参附注射液#</a>（SF）是由宋代中医古籍<a href='/topic/show?id=4ea712664813' target=_blank 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style='color:#2F92EE;'>#氧化应激#</a>。这些反应最终导致急性或慢性排斥反应，并可能导致<a href='/topic/show?id=fe1b81500a3' target=_blank style='color:#2F92EE;'>#肝衰竭#</a>。, objectTitle=J Ethnopharmacol：参附注射液通过JAK2/STAT3途径诱导铁死亡改善肝脏缺血再灌注损伤, objectType=article, longId=874740, objectId=f11e8e474076, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20221229/1672303193754_2570354.jpg, objectUrl=/article/show_article.do?id=f11e8e474076, replyNumber=0, likeNumber=35, createdTime=2025-05-06, rootId=0, userName=侠胆医心, userId=f63e4754896, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=威斯康星, moduleDTOList=[ModuleDTO(moduleId=f11e8e474076, moduleTitle=J Ethnopharmacol：参附注射液通过JAK2/STAT3途径诱导铁死亡改善肝脏缺血再灌注损伤, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=f11e8e474076)], followStatus=false, userIsMember=false, type=1, lengthMark=1), GetTopicListResponse(id=2256998, encodeId=7bff2256998ac, content=<a href='/topic/show?id=049b86109ff' target=_blank 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<a href='/topic/show?id=4cfd111e08e3' target=_blank style='color:#2F92EE;'>#气道上皮屏障#</a> <a href='/topic/show?id=ea82111e099c' target=_blank style='color:#2F92EE;'>#补肺益肾方#</a> <a href='/topic/show?id=9753111e106c' target=_blank style='color:#2F92EE;'>#SIRT1/AMPK/FOXO3信号#</a>, objectTitle=Chin Med：补肺益肾方通过Sirt1/AMPK/Foxo3信号通路增强自噬，保护气道上皮屏障，改善COPD, objectType=article, longId=815311, objectId=7b28815311ac, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20240229/1709184324314_5610093.jpg, objectUrl=/article/show_article.do?id=7b28815311ac, replyNumber=0, likeNumber=201, createdTime=2024-02-29, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=7b28815311ac, moduleTitle=Chin Med：补肺益肾方通过Sirt1/AMPK/Foxo3信号通路增强自噬，保护气道上皮屏障，改善COPD, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=7b28815311ac)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2186414, encodeId=8264218641478, content=<a href='/topic/show?id=fe1b81500a3' target=_blank style='color:#2F92EE;'>#肝衰竭#</a> <a href='/topic/show?id=049b86109ff' target=_blank style='color:#2F92EE;'>#自噬#</a>, objectTitle=特别关注｜自噬对肝衰竭的保护作用机制与临床价值, objectType=article, longId=812170, objectId=de138121e0dd, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20230326/1679867598346_4754896.jpeg, objectUrl=/article/show_article.do?id=de138121e0dd, replyNumber=0, likeNumber=0, createdTime=2024-02-07, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=陕西省, moduleDTOList=[ModuleDTO(moduleId=de138121e0dd, moduleTitle=特别关注｜自噬对肝衰竭的保护作用机制与临床价值, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=de138121e0dd)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2178700, encodeId=4fd421e870092, content=<a href='/topic/show?id=049b86109ff' target=_blank style='color:#2F92EE;'>#自噬#</a> 谢谢老师！, objectTitle=自噬, objectType=topic, longId=86109, objectId=null, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/Random/097.jpg, objectUrl=null, replyNumber=0, likeNumber=91, createdTime=2024-01-02, rootId=0, userName=ms2000000147841561, userId=5bf26472850, projectId=1, avatar=, status=1, hasArticle=0, attachment=null, ipAttribution=河北省, moduleDTOList=null, followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=2176255, encodeId=d95f21e6255de, content=<a href='/topic/show?id=4c239032154' target=_blank style='color:#2F92EE;'>#衰老#</a> <a href='/topic/show?id=049b86109ff' target=_blank style='color:#2F92EE;'>#自噬#</a> <a href='/topic/show?id=053d2148601' target=_blank style='color:#2F92EE;'>#中医药#</a> <a href='/topic/show?id=a92c29945eb' target=_blank style='color:#2F92EE;'>#六味地黄丸#</a> <a href='/topic/show?id=f42e10895349' target=_blank style='color:#2F92EE;'>#绝经后骨质疏松症(PMOP)#</a> <a href='/topic/show?id=10db1089546b' target=_blank style='color:#2F92EE;'>#Yes相关蛋白(YAP)#</a>, objectTitle=Pharm Biol：六味地黄丸通过YAP-自噬轴延缓骨髓间充质干细胞(BMSC)衰老，减轻卵巢切除所致骨质流失, objectType=article, longId=806197, objectId=951c80619e22, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/20231221/1703090245072_5610093.jpg, objectUrl=/article/show_article.do?id=951c80619e22, replyNumber=0, likeNumber=174, createdTime=2023-12-21, rootId=0, userName=梅斯管理员, userId=cade5395722, projectId=1, avatar=, status=1, hasArticle=1, attachment=null, ipAttribution=上海, moduleDTOList=[ModuleDTO(moduleId=951c80619e22, moduleTitle=Pharm Biol：六味地黄丸通过YAP-自噬轴延缓骨髓间充质干细胞(BMSC)衰老，减轻卵巢切除所致骨质流失, moduleType=article, hrefUrl=https://www.medsci.cn/article/show_article.do?id=951c80619e22)], followStatus=false, userIsMember=false, type=null, lengthMark=0), GetTopicListResponse(id=2170403, encodeId=335e21e0403a7, content=<a href='/topic/show?id=049b86109ff' target=_blank style='color:#2F92EE;'>#自噬#</a> 喝点牛奶洗面奶, objectTitle=自噬, objectType=topic, longId=86109, objectId=null, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/Random/097.jpg, objectUrl=null, replyNumber=0, likeNumber=123, createdTime=2023-11-23, rootId=0, userName=ms2000000147841561, userId=5bf26472850, projectId=1, avatar=, status=1, hasArticle=0, attachment=null, ipAttribution=河北省, moduleDTOList=null, followStatus=false, userIsMember=false, type=1, lengthMark=0), GetTopicListResponse(id=2164156, encodeId=020721641565c, content=<a href='/topic/show?id=049b86109ff' target=_blank style='color:#2F92EE;'>#自噬#</a> 好记性不如烂笔头, objectTitle=自噬, objectType=topic, longId=86109, objectId=null, topicUrl=null, isHasObj=0, objectCover=https://img.medsci.cn/Random/097.jpg, objectUrl=null, replyNumber=0, likeNumber=124, createdTime=2023-10-22, rootId=0, userName=ms2000000147841561, userId=5bf26472850, projectId=1, avatar=, status=1, hasArticle=0, attachment=null, ipAttribution=河北省, moduleDTOList=null, followStatus=false, userIsMember=false, type=1, lengthMark=0)] 梅斯话题小助手

自噬的两面，让它永远是正面的

2020-05-29

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#tRNA# #自噬# #tDR#

2025-07-21发表于上海

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#自噬# #慢性炎症# #WSTF蛋白#

2025-07-03发表于上海

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全文收起 #参附注射液#（SF）是由宋代中医古籍#《严氏济生方》#中记载的参附汤研制而成的中药复方制剂，由#人参#和#附子#两味中药组成。SF在中医中用于治疗#厥证#（与现代休克相对应），以其回阳、益气、救脱的作用而闻名。SF对脊髓、脑、小肠、肾脏和心脏等器官的失血性休克和I/R损伤引起的多器官#再灌注损伤#具有保护作用。肝#缺血再灌注损伤#（HIRI）是外科手术后不可避免的挑战。肝脏中#活性氧#（ROS）的积累，沿着#缺血/再灌注#（I/R）引发的炎症反应，启动一系列有害的先天免疫反应，导致肝细胞死亡、#自噬#、循环障碍、能量代谢失调和#氧化应激#。这些反应最终导致急性或慢性排斥反应，并可能导致#肝衰竭#。

J Ethnopharmacol：参附注射液通过JAK2/STAT3途径诱导铁死亡改善肝脏缺血再灌注损伤

2025-05-06发表于威斯康星

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#自噬# #睾丸#

干货！睾丸主要细胞的自噬及其研究进展

2025-03-20发表于陕西省

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#临床试验# #IL-6# #自噬# #桂枝茯苓胶囊# #网络药理学分析# #硼替佐米诱导的周围神经病变#

Phytomedicine：桂枝茯苓胶囊可通过降低白细胞介素-6水平调节mTOR通路诱导的自噬来缓解硼替佐米所致的周围神经病变

2025-02-28发表于陕西省

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#阿尔茨海默病# #自噬# #细胞焦亡# #郁金# #PINK1/Parkin通路#

Phytomedicine：郁金提取物通过PINK1/Parkin介导的自噬减轻阿尔茨海默病的认知缺陷，抑制焦亡

2025-02-17发表于陕西省

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#衰老# #自噬#

Nature Aging：为何男性衰老更快？分子伴侣介导自噬（CMA）的性别特异性解析

2025-02-11发表于陕西省

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#细胞凋亡# #自噬# #肿瘤坏死因子# #溃疡性结肠炎# #肠屏障# #加减交气散#

Phytomedicine：加减交气散增强慢性溃疡性结肠炎上皮细胞自噬，抑制TNF触发的细胞凋亡

2024-12-15发表于上海

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#肝细胞癌# #细胞凋亡# #自噬# #中医药# #消癌解毒方#

J Ethnopharmacol：消癌解毒方通过AKT/mTOR通路刺激肝癌细胞自噬，降低肝癌细胞存活，诱导凋亡

2024-11-28

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#细胞凋亡# #自噬# #肝损伤# #斑蝥素# #DDIT4#

Front Pharmacol：DDIT4/mTOR信号通路介导斑蝥素诱导的肝毒性和细胞损伤

2024-11-21发表于陕西省

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#自噬# #黄芪# #当归# #细胞焦亡# #脑缺血/再灌注损伤# #AMPK/mTOR通路#

J Ethnopharmacol：黄芪-当归药对通过AMPK/mTOR信号通路促进大鼠大脑中动脉闭塞/再灌注后的自噬活性减轻焦亡

2024-10-29发表于上海

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#胶质瘤# #自噬# #云南白药# #坏死性凋亡#

J Ethnopharmacol：云南白药通过诱导自噬依赖性坏死性凋亡发挥抗胶质瘤活性

2024-08-07发表于上海

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#胰腺炎# #自噬#

eGastroenterology：自噬在胰腺炎中的作用

2024-05-31发表于上海

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#骨髓间充质干细胞# #树突状细胞# #自噬# #外泌体# #呼吸道合胞病毒#

J Ethnopharmacol：五虎汤对RSV诱导外泌体处理树突状细胞功能和自噬的影响

2024-05-30发表于上海

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#自噬# #慢性阻塞性肺病# #气道上皮屏障# #补肺益肾方# #SIRT1/AMPK/FOXO3信号#

Chin Med：补肺益肾方通过Sirt1/AMPK/Foxo3信号通路增强自噬，保护气道上皮屏障，改善COPD

2024-02-29发表于上海

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#肝衰竭# #自噬#

特别关注｜自噬对肝衰竭的保护作用机制与临床价值

2024-02-07发表于陕西省

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#自噬# 谢谢老师！

2024-01-02发表于河北省

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#衰老# #自噬# #中医药# #六味地黄丸# #绝经后骨质疏松症(PMOP)# #Yes相关蛋白(YAP)#

Pharm Biol：六味地黄丸通过YAP-自噬轴延缓骨髓间充质干细胞(BMSC)衰老，减轻卵巢切除所致骨质流失

2023-12-21发表于上海

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#自噬# 喝点牛奶洗面奶

2023-11-23发表于河北省

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#自噬# 好记性不如烂笔头

2023-10-22发表于河北省

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